SUPERDROL is a brand name for the anabolic steroid methyldrostanolone. 

Also called methasterone. Methyldrostanolone is a potent oral anabolic agent not marketed as a commercial medical product. The drug was first mentioned in medical reference books in 1960.

The chemical structure of the drug is very close to Masteron , the difference is the additional c-17 alpha methyl group, a modification that gives this steroid high availability for oral administration.  

The effective dosage of methyldrostanolone is in the range of 20-35mg per day for men. At this dosage level, it has a good anabolic effect , which is usually accompanied by fat loss and the appearance of muscle expression. With properly selected dosages, in athletes who have not taken anabolic steroids, muscle gain can be up to 5 kg / month and sometimes more. Those who are familiar with steroids will have less muscle gain. 

It is advisable to combine this drug with nandrolone intake. 

Since this steroid has a very high ratio of anabolic to androgenic effects, it may be of interest to female bodybuilders. In fact, methyldrostenolone is less androgenic than Winstrol and Primobolan, which are popular with most bodybuilders. Women are advised not to increase the dosage above 5 mg / day.

The confusion surrounding Superdrol is due to the unfortunate name of this drug, which was apparently chosen for advertising reasons. The idiot who coined the name ” superdrol “, which clearly indicates the relationship of this substance with oxymetholone ( Anadrol ), has demonstrated his absolute illiteracy in biochemistry. Indeed, both of these drugs are androgenic steroids based on 5-alpha reductase , but other than that, they have nothing in common.     

Superdrol was known long before this strange name came up. Personally, I learned about it from a discussion about another IP laboratory drug with an equally unfortunate name – “oral Masteron”, which turned out to be a simple mestanolone (17-alpha-methyl dihydrotestosterone ) . In fact, mestanolone is an oral dihydrotestosterone – assuming, of course, that the addition of the 17-alpha-methyl group suggests that this drug is an oral variant of the main steroid, although this is not entirely true. Then I noted that in order to be called “oral Masteron “, this substance had to be 2-alpha-methyl mestanolone or, better yet, 17-alpha-methyl drostanolone ( drostanolone is called Masteron ). This is what we named this substance – 17-alpha-methyl drostanolone . It was several years ago. It seems doubtful that this drug has not been researched several decades before, so it likely has a much longer history than we think.     

From all that has been said, we can conclude that ” superdrol ” is actually the result of combining drostanolone and mestanolone , since it includes the 2-alpha-methyl group of drostanolone and the 17-alpha-methyl group of mestanolone . And oxymetholone is a completely different substance that differs from superdrol in that it includes a 2-hydroxymethylene group instead of a 2-methyl one. The methyl group is completely inert because it is non-polar . It does not impart any special biochemical characteristics to the substance, forming a simple steric mass, and this is precisely its purpose. This mass is a steric hindrance for the 3-alpha and 3-beta-hydroxysteroid dehydrogenase enzymes , therefore, unlike mestanolone , superdrol is not deactivated as quickly in muscle tissues. Mestanolone is almost unsuitable as an anabolic, since it deactivates very quickly, breaking down into 3-hydroxy metabolites. The 2-methyl group weakens the bonds between the enzymes that cause such a reaction and slows down the rate of deactivation, therefore superdrol , unlike mestanolone , exhibits some anabolic activity.        

Oxymetholone contains a hydroxylated carbon bonded to another carbon to form a chemically reactive polar group. In addition, this carbon has a double bond with the sterane nucleus , which increases the reactivity of the oxygen atom. Although the mechanism of action of these bonds has not yet been fully understood, it can be argued that they give oxymetholone some unique properties, which is most likely explained by the interaction of this substance with other structures with which most anabolic androgenic steroids do not interact at all or do so in a very limited extent.

Anabolic activity: Since superdrol contains a 17-alpha-methyl group, this substance is less susceptible to metabolic deactivation and does not form 17-ketosteroids; the likelihood of 16-hydroxylation is also low. It follows that superdrol may remain active longer than drostanolone and is excreted more slowly from the body. Unfortunately, the 2-methyl group also weakens bonds with the androgen receptor, which is exacerbated by the presence of a 17-alpha-methyl group in superdrol . For this reason, the effectiveness of Superdrol is significantly reduced, bringing this substance closer to drostanolone in terms of the level of anabolic activity . So superdrol cannot be considered an effective tool for building muscle – it is only suitable for men of short stature and those who do not yet have experience using other anabolic androgenic steroids. This puts superdrol in some other weak oral androgenic steroid having no flavoring effect – such as Anavar (oxandrolone) Winstrol® (Stanozol) and Halotestin (Ftoroksimesteron).    

Androgenic activity: In comparison with the aforementioned weak steroid, androgenic activity superdrol significantly lower than that of Halotestin , but much higher than that of Winstrol and Anavar . This is due to the fact that, despite the increased activity of the drug in comparison with mestanolone , deactivation occurs faster in muscle tissue (the 2-methyl group lowers, but does not completely exclude the reduction of 3-keto function). Non-deactivated dihydrotestosterone does not provide the same level of activity in muscles as in those tissues that are targeted by androgenic steroids, despite the fact that the opposite is widely believed .

Although young, healthy men rarely experience side effects when taking androgenic steroids, those who have reason to fear these side effects should choose Anavar or Winstrol over Superdrol. However, many athletes claim that using the more potent androgenic steroids increases muscle density when the body fat is low. While this is not true for everyone, it can be assumed that superdrol has a similar effect. In this case, Superdrol is preferred over the other oral steroids mentioned herein. More details here

Estrogenic and Progestogenic Activity: Like most 5-alpha reductase steroids, Superdrol is not estrogenic. Mestanolone and drostanolone also have no aromatizing effect. The manufacturers of these substances like to emphasize that they do not have the estrogenic effects inherent in oxymetholone , but we must not forget that , firstly, superdrol has NOTHING to do with oxymetholone , and secondly, it has not yet been proven that the estrogenic effects of oxymetholone are precisely estrogenic in nature: despite the hype raised around this phenomenon, when taking oxymetholone in combination with other anabolic androgenic steroids, estrogenic effects are very weak, and if taken separately, they do not appear at all. Whether this substance exhibits anti-estrogenic activity like drostanolone remains unclear. I wouldn’t count on it.    

Hepatic toxicity: The hepatotoxicity of this drug is quite high , which may be why such substances were not previously advertised or considered as suitable for pharmaceutical use. Personally, in all cases of superdrol intake (four courses of 40 / mg per day for 6 weeks), I observed a significant increase in the level of toxins in the liver compared to the periods of taking other common oral steroids at the same ( dianabol ) or even higher doses ( Anavar , Anadrol , Winstrol ). Therefore, it is recommended to take no more than 30-40 mg of Superdrol per day for no longer than 6 weeks. If the specified dose or the period of taking the drug is exceeded, it is necessary to regularly measure the level of toxins in the liver.  

Application: For those with a history of steroid use, I think it is obvious that Superdrol should only be used in extreme cases – if only because for the same money you can buy much more suitable drugs for building muscle mass. I would recommend not taking Superdrol alone, in combination with other oral steroids and in the last week of the cycle, like most other similar drugs, with the exception of Halotestin . This is due to the fact that most 17-alpha-alkylated androgenic steroids increase the density of the glucocorticoid receptor and, as a result, lead to an accelerated reduction in muscle mass upon completion of the course of administration. The increased risk of hepatotoxic side effects is another reason not to take Superdrol in combination with other oral steroids.